Obagi’s Tretinoin Cream 0.05% contains a moderate concentration of tretinoin, the active ingredient most prescribed by doctors to improve visible signs of aging like fine lines, wrinkles and discoloration. This active ingredient stimulates collagen production and accelerates skin-cell turnover, making it an effective acne treatment as well. This formulation features a creamy base for extra hydration. Apply in the evening after cleansing. Allow cream to fully absorb before applying moisturizer.