Obagi Nu-Derm products focus on correcting photodamage on the skin, which is caused by exposure to UVA and UVB rays from the sun. From the excessive exposure, skin cell turnover is decreased and an imbalance occurs between growth of new healthy cells and old damaged cells. Then collagen and elastin begin to break down and cause fine lines, wrinkles, sagging, and uneven coloring. People who have experience sunburns, daily sun exposure, hormonal changes, stress and environmental pollution, then there are signs of premature aging and acne flare-ups. The Nu-Derm System has consistently shown clinically significant results with all skin types and conditions. According to a clinical study of 301 patients, “in only 12 weeks, patients with mild to moderate photo-damaged skin enjoyed greater improvements in key measures of photo damage, including wrinkles, firmness and hyperpigmentation.” There are four specific phases of skin trasformation with the Nu-Derm System. The first phase, a more even toned appearance of the skin is expected. Possible side effects are itching, dryness, and redness as your skin adapts. In the second phase, collagen is stimulated, and normal healthy cells begin to produce to create smoother, softer, clearer skin. In the third phase, skin is clearer, firmer, and tighter with a healthy glow. In the fourth phase, your skin will be transformed by the system that looks and acts younger and healthier with continued use.